Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean

  title={Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean},
  author={Victor R. Grann and Elad Ziv and Cecil K. Joseph and Alfred I. Neugut and Ying Wei and Judith S. Jacobson and Marshall S Horwitz and Natalie M. Bowman and Kenneth Beckmann and Dawn L. Hershman},
  journal={British Journal of Haematology},
  pages={288 - 293}
Neutropenia associated with race/ethnicity has essentially been unexplained and, although thought to be benign, may affect therapy for cancer or other illnesses. A recent study linked a single nucleotide polymorphism (SNP) (rs2814778) in the Duffy antigen/receptor chemokine gene (DARC) with white blood cell count. We therefore analysed the association of the rs2814778 CC, TC and TT genotypes with absolute neutrophil count (ANC) among asymptomatic women from the Caribbean, Europe and the United… CONTINUE READING


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