Ductus-dependent fetal cardiac defects contraindicate indomethacin tocolysis.

@article{Saenger1992DuctusdependentFC,
  title={Ductus-dependent fetal cardiac defects contraindicate indomethacin tocolysis.},
  author={Jeff S Saenger and David C Mayer and Lawrence J D'angelo and Elizabeth Manci},
  journal={Journal of perinatology : official journal of the California Perinatal Association},
  year={1992},
  volume={12 1},
  pages={41-7}
}
The hemodynamics of critical aortic stenosis in the fetus make it a ductus-dependent cardiac defect because the ductus arteriosus supplies blood not only to the descending aorta but also to the aortic arch and coronary vessels. In utero closure of the ductus arteriosus has been reported in association with tetralogy of Fallot, truncus arteriosus, maternal… CONTINUE READING