Ductile sliding between mineral crystals followed by rupture of collagen crosslinks: experimentally supported micromechanical explanation of bone strength.

@article{Fritsch2009DuctileSB,
  title={Ductile sliding between mineral crystals followed by rupture of collagen crosslinks: experimentally supported micromechanical explanation of bone strength.},
  author={Andreas Fritsch and Christian Hellmich and Luc Dormieux},
  journal={Journal of theoretical biology},
  year={2009},
  volume={260 2},
  pages={230-52}
}
There is an ongoing discussion on how bone strength could be explained from its internal structure and composition. Reviewing recent experimental and molecular dynamics studies, we here propose a new vision on bone material failure: mutual ductile sliding of hydroxyapatite mineral crystals along layered water films is followed by rupture of collagen crosslinks. In order to cast this vision into a mathematical form, a multiscale continuum micromechanics theory for upscaling of elastoplastic… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 41 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 126 references

Mechanical properties of sintered hydroxyapatite for prosthetic applications

  • M. Akao, H. Aoki, K. Kato
  • Journal of Materials Science,
  • 1981
Highly Influential
5 Excerpts

Bone as a composite material: The role of osteons as barriers to crack growth in compact bone

  • F. J. O’Brien, D. Taylor, T. C. Lee
  • International Journal of Fatigue,
  • 2007
Highly Influential
4 Excerpts

Structural morphology and constitutive behavior of microheterogeneous materials

  • A. Zaoui
  • Continuum micromechanics,
  • 1997
Highly Influential
14 Excerpts

Consistent tangent operators for rate- independent elastoplasticity

  • J. C. Simo, R. L. Taylor
  • Computer Methods in Applied Mechanics and…
  • 1985
Highly Influential
4 Excerpts

A study of dense mineralized tissue by neutron diffraction

  • S. Lees, L. C. Bonar, H. A. Mook
  • International Journal of Biological…
  • 1984
Highly Influential
6 Excerpts

Similar Papers

Loading similar papers…