Duchenne de Boulogne and the Muscle Biopsy

  title={Duchenne de Boulogne and the Muscle Biopsy},
  author={K. R. Nelson and C. Genain},
  journal={Journal of Child Neurology},
  pages={315 - 315}
ment was inspired by his experience with &dquo;Mideldorff’s harpoon,&dquo; a device used in Germany to study trichinosis in human muscles, but found by Duchenne to be painful and to retrieve inadequate specimens. Mindful of the complications encountered by Griesinger and Billroth following the first open muscle biopsy (in a case of pseudohypertrophic paralysis), Duchenne wrote: This is why I have designed a little instrument that I called the 
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