Dual-subtype FIV vaccine (Fel-O-Vax® FIV) protection against a heterologous subtype B FIV isolate

@article{Pu2005DualsubtypeFV,
  title={Dual-subtype FIV vaccine (Fel-O-Vax{\textregistered} FIV) protection against a heterologous subtype B FIV isolate},
  author={Ruiyu Pu and James K. Coleman and James G Coisman and Eiji Sato and Taishi Tanabe and Maki Arai and Janet K. Yamamoto},
  journal={Journal of Feline Medicine and Surgery},
  year={2005},
  volume={7},
  pages={65 - 70}
}
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57 Citations

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The challenges facing vaccine development, the current state of knowledge and future prospects for FIV vaccination are reviewed.
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An updated nation-wide epidemiological survey of feline immunodeficiency virus (FIV) infection was conducted in Japan and a geographic distribution of four subtypes (A, B, C and D) of FIV in Japan was disclosed.
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This data indicates that FIV infection in cats is a natural infection of domestic felid populations which results in a chronic and progressive acquired immunodeficiency syndrome and that vaccination against FIV is a viable treatment option for these patients.
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It is important that the key determinants of immunity induced by this vaccine are discovered; such data would compliment vaccine field efficacy studies and provide the basis to make informed recommendations on its use.
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