Dual specificity of activin type II receptor ActRIIb in dorso-ventral patterning during zebrafish embryogenesis.

@article{Nagaso1999DualSO,
  title={Dual specificity of activin type II receptor ActRIIb in dorso-ventral patterning during zebrafish embryogenesis.},
  author={Hideyuki Nagaso and Atsushi Suzuki and Masazumi Tada and N Ueno},
  journal={Development, growth & differentiation},
  year={1999},
  volume={41 2},
  pages={
          119-33
        }
}
  • Hideyuki Nagaso, Atsushi Suzuki, +1 author N Ueno
  • Published in
    Development, growth…
    1999
  • Biology, Medicine
  • Members of the transforming growth factor-beta (TGF-beta) superfamily are thought to regulate specification of a variety of tissue types in early embryogenesis. These effects are mediated through a cell surface receptor complex, consisting of two classes of ser/thr kinase receptor, type I and type II. In the present study, cDNA encoding zebrafish activin type II receptors, ActRIIa and ActRIIb was cloned and characterized. Overexpression of ActRIIb in zebrafish embryos caused dorsalization of… CONTINUE READING

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