Dual roles for the trimeric G protein Go in asymmetric cell division in Drosophila.

@article{Katanaev2006DualRF,
  title={Dual roles for the trimeric G protein Go in asymmetric cell division in Drosophila.},
  author={Vladimir L Katanaev and Andrew Tomlinson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 17},
  pages={
          6524-9
        }
}
During asymmetric division, a cell polarizes and differentially distributes components to its opposite ends. The subsequent division differentially segregates the two component pools to the daughters, which thereby inherit different developmental directives. In Drosophila sensory organ precursor cells, the localization of Numb protein to the cell's anterior cortex is a key patterning event and is achieved by the combined action of many proteins, including Pins, which itself is localized… CONTINUE READING

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