Dual role of sequence-dependent DNA curvature in nucleosome stability: the critical test of highly bent Crithidia fasciculata DNA tract.

@article{Scipioni2004DualRO,
  title={Dual role of sequence-dependent DNA curvature in nucleosome stability: the critical test of highly bent Crithidia fasciculata DNA tract.},
  author={Anita Scipioni and Sabrina Pisano and Claudio Anselmi and Maria Isabel Savino and Pasquale De Santis},
  journal={Biophysical chemistry},
  year={2004},
  volume={107 1},
  pages={7-17}
}
In spite of the knowledge of the nucleosome molecular structure, the role of DNA intrinsic curvature in determining nucleosome stabilization is still an open question. In this paper, we describe a general model that allows the prediction of the nucleosome stability, tested on 83 different DNA sequences, in surprising good agreement with the experimental data, carried out in ours as well as in many other laboratories. The model is based on the dual role of DNA curvature in nucleosome… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
9 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…