Dual role of heat shock proteins as regulators of apoptosis and innate immunity.

@article{Joly2010DualRO,
  title={Dual role of heat shock proteins as regulators of apoptosis and innate immunity.},
  author={Anne-Laure Joly and Guillaume Wettstein and Gr{\'e}goire Mignot and François Ghiringhelli and Carmen Garrido},
  journal={Journal of innate immunity},
  year={2010},
  volume={2 3},
  pages={238-47}
}
Stress or heat shock proteins (HSPs) 70 and 90 are powerful chaperones whose expression is induced in response to a wide variety of physiological and environmental insults. These proteins have different functions depending on their intracellular or extracellular location. Intracellular HSPs have a protective function. They allow the cells to survive potentially lethal conditions. The cytoprotective functions of HSPs can largely be explained by their anti-apoptotic properties. HSP70 and HSP90… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 94 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 52 references

Similar Papers

Loading similar papers…