Dual regulation by protein kinase C of the muscarinic response in Xenopus oocytes

@article{LupuMeiri1989DualRB,
  title={Dual regulation by protein kinase C of the muscarinic response in Xenopus oocytes},
  author={Monica Lupu-Meiri and Hagit Shapira and Y Oron},
  journal={Pfl{\"u}gers Archiv},
  year={1989},
  volume={413},
  pages={498-504}
}
Muscarinic stimulation of follicle-enclosed oocytes ofXenopus laevis results in a complex response that involves both depolarizing and hyperpolarizing currents (Dascal and Landau 1980). We studied the involvement of protein kinase C (PK-C1) in the regulation of the acetylcholine-evoked rapid (D1) and of the slow (D2) depolarizing chloride (Cl−) currents. In oocytes maintained at −100 mV [the reversal potential of potassium (K+) ions] under two electrode voltage clamp, the PK-C activator 4… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 23 references

Similar Papers

Loading similar papers…