Dual regulation by phospho-OmpR of ssrA/B gene expression in Salmonella pathogenicity island 2.

@article{Feng2003DualRB,
  title={Dual regulation by phospho-OmpR of ssrA/B gene expression in Salmonella pathogenicity island 2.},
  author={Xiuhong Feng and Ricardo Oropeza and Linda J Kenney},
  journal={Molecular microbiology},
  year={2003},
  volume={48 4},
  pages={1131-43}
}
Expression of genes located on Salmonella pathogenicity island 2 (SPI-2) is required for systemic infection in mice. This region encodes a type III secretion system, secreted effectors and the two-component regulatory system SsrA/B (also referred to as SpiR), as well as additional uncharacterized genes. In the present work, we demonstrate that phospho-OmpR (OmpR-P) functions as an activator at the spiC-ssrA/B locus. There are two promoters at spiR; one is upstream of ssrA and the other upstream… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 59 extracted citations

Control of Salmonella pathogenicity island-2 gene expression.

Current opinion in microbiology • 2009
View 6 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…