Dual-modality gene reporter for in vivo imaging.

@article{Patrick2014DualmodalityGR,
  title={Dual-modality gene reporter for in vivo imaging.},
  author={P Stephen Patrick and Jayne Hammersley and Louiza Loizou and Mikko I Kettunen and Tiago B Rodrigues and De-en Hu and Sui-Seng Tee and Robin Hesketh and S Kathleen Lyons and Dmitry Soloviev and David Yestin Lewis and Silvio Aime and Sandra M Fulton and Kevin M Brindle},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2014},
  volume={111 1},
  pages={415-20}
}
The ability to track cells and their patterns of gene expression in living organisms can increase our understanding of tissue development and disease. Gene reporters for bioluminescence, fluorescence, radionuclide, and magnetic resonance imaging (MRI) have been described but these suffer variously from limited depth penetration, spatial resolution, and sensitivity. We describe here a gene reporter, based on the organic anion transporting protein Oatp1a1, which mediates uptake of a clinically… CONTINUE READING
Highly Cited
This paper has 54 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Organic anion-transporting polypeptide 1B3 as a dual reporter gene for fluorescence and magnetic resonance imaging

FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 2018
View 4 Excerpts
Highly Influenced

Optoacoustic Detection of Early Therapy-Induced Tumor Cell Death Using a Targeted Imaging Agent.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2017
View 1 Excerpt

55 Citations

01020'14'15'16'17'18'19
Citations per Year
Semantic Scholar estimates that this publication has 55 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 36 references

Hepatic uptake of the magnetic resonance imaging contrast agent Gd-EOB-DTPA: role of human organic anion transporters.

Drug metabolism and disposition: the biological fate of chemicals • 2010
View 3 Excerpts
Highly Influenced

Noninvasive molecular imaging using reporter genes.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine • 2013
View 3 Excerpts

Quantitative evaluation of MRI-based tracking of ferritinlabeled endogenous neural stem cell progeny in rodent brain

G Vande Velde
Neuroimage • 2012
View 2 Excerpts

Similar Papers

Loading similar papers…