Dual mechanisms for nitric oxide control of large arteries in the estuarine crocodile Crocodylus porosus.

@article{Broughton2007DualMF,
  title={Dual mechanisms for nitric oxide control of large arteries in the estuarine crocodile Crocodylus porosus.},
  author={Brad R. S. Broughton and John A. Donald},
  journal={The Journal of experimental biology},
  year={2007},
  volume={210 Pt 1},
  pages={129-37}
}
In reptiles, accumulating evidence suggests that nitric oxide (NO) induces a potent relaxation in the systemic vasculature. However, very few studies have examined the source from which NO is derived. Therefore, the present study used both anatomical and physiological approaches to establish whether NO-mediated vasodilation is via an endothelial or neural NO pathway in the large arteries of the estuarine crocodile Crocodylus porosus. Specific endothelial nitric oxide synthase (NOS) staining was… CONTINUE READING
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