Dual isotope test for assessing beta-carotene cleavage to vitamin A in humans.

@article{Hickenbottom2002DualIT,
  title={Dual isotope test for assessing beta-carotene cleavage to vitamin A in humans.},
  author={Sabrina J Hickenbottom and Shawna L Lemke and Stephen R. Dueker and Yumei Lin and Jennifer R. Follett and Colleen Carkeet and Bruce A. Buchholz and John S. Vogel and Andrew Clifford},
  journal={European journal of nutrition},
  year={2002},
  volume={41 4},
  pages={141-7}
}
BACKGROUND The ability of beta-carotene to deliver bioactive retinoids to tissues is highly variable. A clearer understanding of the environmental and genetic factors that modulate the vitamin A potential of beta-carotene is needed. AIM OF STUDY Assess the vitamin A value of orally administered beta-carotene relative to a co-administered reference dose of preformed vitamin A. METHODS Equimolar doses (30 micromol) of hexadeuterated D6 beta-carotene and D6 retinyl acetate were orally co… CONTINUE READING
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