Dual intramolecular hydrogen bond as a switch for inducing ground and excited state intramolecular double proton transfer in doxorubicin: an excitation wavelength dependence study.

@article{Rana2011DualIH,
  title={Dual intramolecular hydrogen bond as a switch for inducing ground and excited state intramolecular double proton transfer in doxorubicin: an excitation wavelength dependence study.},
  author={Dipak Kumar Rana and Sayaree Dhar and Arindam Sarkar and Subhash Chandra Bhattacharya},
  journal={The journal of physical chemistry. A},
  year={2011},
  volume={115 33},
  pages={9169-79}
}
This paper investigates how solution conditions, especially solvent polarity and hydrogen bonding, influence the fluorescence of an anticancer drug, doxorubicin hydrochloride (DOX). When excited at 480 nm, this molecule shows single fluorescence. However, when excited at 346 nm, it shows dual fluorescence. The ground and excited state intramolecular double… CONTINUE READING