Dual hypopigmentary effects of punicalagin via the ERK and Akt pathways.

@article{Shin2017DualHE,
  title={Dual hypopigmentary effects of punicalagin via the ERK and Akt pathways.},
  author={Jun Seob Shin and Jun Hee Cho and Hana Lee and Hyo-soon Jeong and M Kim and Hye-young Yun and Nyoun Soo Kwon and Dong-Seok Kim},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={2017},
  volume={92},
  pages={122-127}
}
Punicalagin is a phenolic compound with antioxidant properties. However, the effects of punicalagin on melanin synthesis have been poorly evaluated. Therefore, we investigated the effects of punicalagin on melanogenesis in Mel-Ab cells. Punicalagin significantly inhibited melanin synthesis in a dose-dependent manner. In accordance with the melanin content… CONTINUE READING