Dual function of the alcohol dehydrogenase of Drosophila melanogaster: ethanol and acetaldehyde oxidation by two allozymes ADH-71k and ADH-F

@article{Eisses1985DualFO,
  title={Dual function of the alcohol dehydrogenase of Drosophila melanogaster: ethanol and acetaldehyde oxidation by two allozymes ADH-71k and ADH-F},
  author={Karel Th. Eisses and Willem G. E. J. Schoonen and Wim J M Aben and Willem Scharloo and George E. W. Th{\"o}rig},
  journal={Molecular and General Genetics MGG},
  year={1985},
  volume={199},
  pages={76-81}
}
Until recently the alcohol dehydrogenase of Drosophila melanogaster was thought to act only in the first step of primary alcohol oxidation, producing an aldehyde. Instead, acetic acid is the main product of a two-step process. A rapid procedure was developed for the isolation and purification of two allozymes. The thermostability of the purified enzymes was found to be very different, t 1/2 at 35°C, being 45 min and 130 min for ADH-F and ADH-71k respectively. The kinetic parameters of ethanol… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Allozymes and biochemical adaptation. In: Kerkut GK, Gilbert LI (eds) Comprehensive insect physiology

  • AJ Zera, RK Koehn, JG Hall
  • Biochemistry and Pharmacology,
  • 1985

Differences in ethanol oxidation by alcohol dehydrogenase of Drosophila simulans and Drosophila melanogaster (submitted to Evolution

  • Eisses KTh, Schoonen WGEJ, W Scharloo
  • GEW
  • 1985

Metabolism of secondary alcohols in Drosophila melanogaster

  • PWH Heinstra, KTh Eisses, W Scharloo
  • GEW
  • 1985
1 Excerpt

tabolism of secondary alcohols in Drosophila melanogaster : Effects on alcohol dehydrogenase

  • Heinstra PWH, Eisses KTh, W Scharloo
  • 1985

Drosophila melanogaster alcohol dehydrogenase: substrate stereospecificity of the Adh-F alleloenzyme

  • R Hovik, J-O Winberg, JS McKinley-McKee
  • Insect Biochem
  • 1984
1 Excerpt

Regulation of alcohol dehydrogenase in Drosophila melanogaster by dietary alcohol and carbohydrate

  • SW McKechnie, BW Geer
  • Insect Biochem
  • 1984
1 Excerpt

Similar Papers

Loading similar papers…