Dual function of polysialic acid during zebrafish central nervous system development.

@article{Marx2001DualFO,
  title={Dual function of polysialic acid during zebrafish central nervous system development.},
  author={Markus Marx and Ueli Rutishauser and Martin Bastmeyer},
  journal={Development},
  year={2001},
  volume={128 24},
  pages={
          4949-58
        }
}
Polysialic acid (PSA), a carbohydrate epitope attached to the neural cell adhesion molecule, serves as a modulator of axonal interactions during vertebrate nervous system development. We have used PSA-specific antibodies and whole-mount immunocytochemistry to describe the spatiotemporal expression pattern of PSA during zebrafish central nervous system development. PSA is transiently expressed on all cell bodies and, except for the posterior commissure, it is not found on axons. Floorplate cells… CONTINUE READING

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