Dual function of an amino-terminal amphipatic helix in androgen receptor-mediated transactivation through specific and nonspecific response elements.

@article{Callewaert2003DualFO,
  title={Dual function of an amino-terminal amphipatic helix in androgen receptor-mediated transactivation through specific and nonspecific response elements.},
  author={Leen Callewaert and Guy Verrijdt and Valerie Christiaens and Annemie Haelens and Frank Claessens},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 10},
  pages={8212-8}
}
Steroid receptors are transcription factors that, upon binding to their response elements, regulate the expression of several target genes via direct protein interactions with transcriptional coactivators. For the androgen receptor, additional interactions between the amino- and carboxyl-terminal regions have been reported. The first amino acids of the… CONTINUE READING