Dual function of Lactobacillus kefiri DH5 in preventing high-fat-diet-induced obesity: direct reduction of cholesterol and upregulation of PPAR-α in adipose tissue.

@article{Kim2017DualFO,
  title={Dual function of Lactobacillus kefiri DH5 in preventing high-fat-diet-induced obesity: direct reduction of cholesterol and upregulation of PPAR-α in adipose tissue.},
  author={Dong-Hyeon Kim and Dana Jeong and Il-Byeong Kang and Hyunsook Kim and Kwang-Young Song and Kun-Ho Seo},
  journal={Molecular nutrition & food research},
  year={2017},
  volume={61 11}
}
SCOPE Kefir consumption inhibits the development of obesity and non-alcoholic fatty liver disease (NALFD) in mice fed 60% high-fat diet (HFD). To identify the key contributor of this effect, we isolated lactic acid bacteria (LAB) from kefir and examined their anti-obesity properties from in vitro screening and in vivo validation. METHODS AND RESULTS Thirteen kefir LAB isolates were subjected to survivability test using artificial gastrointestinal environment and cholesterol-reducing assay… CONTINUE READING