Dual effects of ouabain on the regulation of proliferation and apoptosis in human umbilical vein endothelial cells: involvement of Na(+)-K(+)-ATPase α-subunits and NF-κB.

Abstract

PURPOSE To elucidate the effect of ouabain on the regulation of proliferation and apoptosis of HUVECs and involvement of different Na(+)-K(+)-ATPase α-subunits and NF-κB. METHODS HUVECs were isolated by collagenase perfusion, and MTT assays and cell cycle analysis were performed to study proliferation. NF-κB expression and function were examined by… (More)

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@article{Ren2014DualEO, title={Dual effects of ouabain on the regulation of proliferation and apoptosis in human umbilical vein endothelial cells: involvement of Na(+)-K(+)-ATPase α-subunits and NF-κB.}, author={Yan-ping Ren and Ming-juan Zhang and Ting Zhang and Ruo-wen Huang}, journal={International journal of clinical and experimental medicine}, year={2014}, volume={7 5}, pages={1214-22} }