Dual effect of ethanol on cell death in primary culture of human and rat hepatocytes.

@article{Castilla2004DualEO,
  title={Dual effect of ethanol on cell death in primary culture of human and rat hepatocytes.},
  author={Rafael Castilla and Ra{\'u}l Mac{\'i}as Gonz{\'a}lez and Dalia Fouad and Enrique Fraga and Jordi Muntan{\'e}},
  journal={Alcohol and alcoholism},
  year={2004},
  volume={39 4},
  pages={290-6}
}
AIMS In-vivo and in-vitro studies have shown that ethanol induces hepatocyte damage. The aim of the present study was to evaluate the effect of a broad range of ethanol concentrations on apoptosis and necrosis in primary culture of human and rat hepatocytes. METHODS Human and rat hepatocytes were isolated from human hepatectomies and male Wistar rats (200-250 g) using the classical collagenase perfusion method. After stabilization of cell culture, ethanol (0-10 mmol/l) was administered and… CONTINUE READING
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Acute and chronic ethanol increases reactive oxygen species generation and decreases viability in fresh , isolated rat hepatocytes

  • S. M. Baileym, C. C. Cunningham
  • Hepatology
  • 1998

Acute and chronic ethanol increases reactive oxygen species generation and decreases viability in fresh, isolated rat

  • S. M. Baileym, C. C. Cunningham
  • hepatocytes. Hepatology
  • 1998

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