Dual effect of cicletanine on the Na+-H+ exchanger in chick embryonic cardiomyocytes.

@article{Samain1999DualEO,
  title={Dual effect of cicletanine on the Na+-H+ exchanger in chick embryonic cardiomyocytes.},
  author={E. Samain and G. Dagher and H. Bouillier and C. Perret and M. T. Droy-lefaix and M. Safar and J. Renaud},
  journal={Journal of cardiovascular pharmacology},
  year={1999},
  volume={33 1},
  pages={
          169-72
        }
}
Na+-H+ exchanger is thought to play an important role in the regulation of the intracellular pH (pHi) and in the cardiac cell injury induced by ischemia and reperfusion. The aim of this study was to assess the effect of cicletanine, an antihypertensive compound in humans, which has been reported to have cardioprotective effect under an ischemia-reperfusion process, on Na+-H+ exchanger activity in ventricular cardiomyocytes isolated from chick embryo. Na+-H+ exchanger activity was assessed by… Expand

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