Dual delivery for stem cell differentiation using dexamethasone and bFGF in/on polymeric microspheres as a cell carrier for nucleus pulposus regeneration.

Abstract

This study aimed to investigate the feasibility of the nanostructured 3D poly(lactide-co-glycolide) (PLGA) constructs, which are loaded with dexamethasone (DEX) and growth factor embedded heparin/poly(L-lysine) nanoparticles via a layer-by-layer system, to serve as an effective scaffold for nucleus pulposus (NP) tissue engineering. Our results demonstrated… (More)
DOI: 10.1007/s10856-012-4563-0

Topics

7 Figures and Tables

Cite this paper

@article{Liang2012DualDF, title={Dual delivery for stem cell differentiation using dexamethasone and bFGF in/on polymeric microspheres as a cell carrier for nucleus pulposus regeneration.}, author={C. Z. Liang and Hongqi Li and Y Q Tao and Xiaoling Zhou and Z. R. Yang and Yufei Xiao and F. C. Li and Bin Han and Q. X. Chen}, journal={Journal of materials science. Materials in medicine}, year={2012}, volume={23 4}, pages={1097-107} }