Dual beta-adrenergic modulation in the immune system: stimulus-dependent effect of isoproterenol on MAPK activation and inflammatory mediator production in macrophages.

@article{Szelnyi2006DualBM,
  title={Dual beta-adrenergic modulation in the immune system: stimulus-dependent effect of isoproterenol on MAPK activation and inflammatory mediator production in macrophages.},
  author={Judith Szel{\'e}nyi and Zsolt Selmeczy and Anna Br{\'o}zik and David Medgyesi and M{\'a}ria Mag{\'o}csi},
  journal={Neurochemistry international},
  year={2006},
  volume={49 1},
  pages={94-103}
}
This is the first study to demonstrate that the interaction between beta-adrenoceptor activation, and the production of inflammatory mediators can be modulated in opposite ways by two inflammatory stimuli, namely, protein kinase C (PKC)-activating phorbol myristyl acetate (PMA) and lipopolysaccharide (LPS). We provided evidence that isoproterenol treatment… CONTINUE READING