Dual analyte immunoassay in neural tube defect and Down's syndrome screening: results of a multicentre clinical trial.

@article{Spencer1993DualAI,
  title={Dual analyte immunoassay in neural tube defect and Down's syndrome screening: results of a multicentre clinical trial.},
  author={Kevin Sim{\~o}es Spencer and James N Macri and Robert W. Anderson and David A. Aitken and Elliot Berry and Jennifer A. Crossley and Peter J W Wood and Edward J. Coombes and Michael Johannes Nicholas Polson Jonathan Stroud and David J. Worthington},
  journal={Annals of clinical biochemistry},
  year={1993},
  volume={30 ( Pt 4)},
  pages={394-401}
}
We report a multicentre clinical field trial of a novel dual analyte enzyme immunoassay method for the simultaneous measurement of alpha-fetoprotein (AFP) and free beta-human choriogonadotropin (hCG) in the same microtitre well. The assay was shown to have good technical performance in the hands of all trial centres, with between assay coefficients of… CONTINUE READING