Dual-Wavelength Imaging of Tumor Progression by Activatable and Targeting Near-Infrared Fluorescent Probes in a Bioluminescent Breast Cancer Model

@inproceedings{Xie2012DualWavelengthIO,
  title={Dual-Wavelength Imaging of Tumor Progression by Activatable and Targeting Near-Infrared Fluorescent Probes in a Bioluminescent Breast Cancer Model},
  author={Bang-Wen Xie and Isabel M. Mol and Stijn Keereweer and Ermond R. van Beek and Ivo Que and Thomas J. A. Snoeks and Alan N. L. Chan and Eric L. Kaijzel and Clemens W. G. M. L{\"o}wik},
  booktitle={PloS one},
  year={2012}
}
Bioluminescence imaging (BLI) has shown its appeal as a sensitive technique for in vivo whole body optical imaging. However, the development of injectable tumor-specific near-infrared fluorescent (NIRF) probes makes fluorescence imaging (FLI) a promising alternative to BLI in situations where BLI cannot be used or is unwanted (e.g., spontaneous transgenic tumor models, or syngeneic mice to study immune effects).In this study, we addressed the questions whether it is possible to detect tumor… CONTINUE READING
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