Dual Role for Pilus in Adherence to Epithelial Cells and Biofilm Formation in Streptococcus agalactiae

@article{KontoGhiorghi2009DualRF,
  title={Dual Role for Pilus in Adherence to Epithelial Cells and Biofilm Formation in Streptococcus agalactiae},
  author={Yoan Konto-Ghiorghi and Emilie Mairey and Adeline Mallet and Guillaume Dum{\'e}nil and Elise Caliot and Patrick Trieu-Cuot and Shaynoor Dramsi},
  journal={PLoS Pathogens},
  year={2009},
  volume={5},
  pages={41 - 57}
}
Streptococcus agalactiae is a common human commensal and a major life-threatening pathogen in neonates. Adherence to host epithelial cells is the first critical step of the infectious process. Pili have been observed on the surface of several gram-positive bacteria including S. agalactiae. We previously characterized the pilus-encoding operon gbs1479-1474 in strain NEM316. This pilus is composed of three structural subunit proteins: Gbs1478 (PilA), Gbs1477 (PilB), and Gbs1474 (PilC), and its… CONTINUE READING
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