Dual RNA-seq of Nontypeable Haemophilus influenzae and Host Cell Transcriptomes Reveals Novel Insights into Host-Pathogen Cross Talk

@inproceedings{Baddal2015DualRO,
  title={Dual RNA-seq of Nontypeable Haemophilus influenzae and Host Cell Transcriptomes Reveals Novel Insights into Host-Pathogen Cross Talk},
  author={Buket Baddal and Alessandro Muzzi and Stefano Censini and Raffaele Adolfo Calogero and Giulia Torricelli and Silvia Guidotti and Anna Rita Taddei and Antonello Covacci and Mariagrazia Pizza and Rino Rappuoli and Marco Soriani and Alfredo Pezzicoli},
  booktitle={mBio},
  year={2015}
}
UNLABELLED The ability to adhere and adapt to the human respiratory tract mucosa plays a pivotal role in the pathogenic lifestyle of nontypeable Haemophilus influenzae (NTHi). However, the temporal events associated with a successful colonization have not been fully characterized. In this study, by reconstituting the ciliated human bronchial epithelium in vitro, we monitored the global transcriptional changes in NTHi and infected mucosal epithelium simultaneously for up to 72 h by dual RNA… CONTINUE READING
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