Dual Infection with HIV and Malaria Fuels the Spread of Both Diseases in Sub-Saharan Africa

@article{AbuRaddad2006DualIW,
  title={Dual Infection with HIV and Malaria Fuels the Spread of Both Diseases in Sub-Saharan Africa},
  author={Laith Jamal Abu-Raddad and Padmaja Patnaik and James G. Kublin},
  journal={Science},
  year={2006},
  volume={314},
  pages={1603 - 1606}
}
Mounting evidence has revealed pathological interactions between HIV and malaria in dually infected patients, but the public health implications of the interplay have remained unclear. A transient almost one-log elevation in HIV viral load occurs during febrile malaria episodes; in addition, susceptibility to malaria is enhanced in HIV-infected patients. A mathematical model applied to a setting in Kenya with an adult population of roughly 200,000 estimated that, since 1980, the disease… Expand
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A better understanding of the interaction between endemic infections and HIV may enhance HIV prevention programs in SSA and summarizes current knowledge of the epidemiology and underlying immunological mechanisms by which endemic infections could impact HIV acquisition. Expand
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