Dual Expression Profile of Type VI Secretion System Immunity Genes Protects Pandemic Vibrio cholerae

@inproceedings{Miyata2013DualEP,
  title={Dual Expression Profile of Type VI Secretion System Immunity Genes Protects Pandemic Vibrio cholerae},
  author={Sarah T. Miyata and Daniel Unterweger and Sydney P. Rudko and Stefan U. Pukatzki},
  booktitle={PLoS pathogens},
  year={2013}
}
The Vibrio cholerae type VI secretion system (T6SS) assembles as a molecular syringe that injects toxic protein effectors into both eukaryotic and prokaryotic cells. We previously reported that the V. cholerae O37 serogroup strain V52 maintains a constitutively active T6SS to kill other Gram-negative bacteria while being immune to attack by kin bacteria. The pandemic O1 El Tor V. cholerae strain C6706 is T6SS-silent under laboratory conditions as it does not produce T6SS structural components… CONTINUE READING
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