Dual Analysis of the Murine Cytomegalovirus and Host Cell Transcriptomes Reveal New Aspects of the Virus-Host Cell Interface

@inproceedings{Lisni2013DualAO,
  title={Dual Analysis of the Murine Cytomegalovirus and Host Cell Transcriptomes Reveal New Aspects of the Virus-Host Cell Interface},
  author={Vanda Jurani{\'c} Lisni{\'c} and Marina Babic Cac and Berislav Lisni{\'c} and Tihana Trsan and Adam L. Mefferd and Chitrangada Das Mukhopadhyay and Charles H Cook and Stipan Jonji{\'c} and Joanne Trgovcich},
  booktitle={PLoS pathogens},
  year={2013}
}
Major gaps in our knowledge of pathogen genes and how these gene products interact with host gene products to cause disease represent a major obstacle to progress in vaccine and antiviral drug development for the herpesviruses. To begin to bridge these gaps, we conducted a dual analysis of Murine Cytomegalovirus (MCMV) and host cell transcriptomes during lytic infection. We analyzed the MCMV transcriptome during lytic infection using both classical cDNA cloning and sequencing of viral… CONTINUE READING

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