Dtrk, a Drosophila gene related to the trk family of neurotrophin receptors, encodes a novel class of neural cell adhesion molecule.

@article{Pulido1992DtrkAD,
  title={Dtrk, a Drosophila gene related to the trk family of neurotrophin receptors, encodes a novel class of neural cell adhesion molecule.},
  author={Diego Pulido and Sonsoles Campuzano and Toshiaki Koda and Juan Modolell and Mariano Barbacid},
  journal={The EMBO journal},
  year={1992},
  volume={11 2},
  pages={391-404}
}
We report the identification and molecular characterization of Dtrk, a Drosophila gene encoding a receptor tyrosine kinase highly related to the trk family of mammalian neurotrophin receptors. The product of the Dtrk gene, gp160Dtrk, is dynamically expressed during Drosophila embryogenesis in several areas of the developing nervous system, including neurons and fasciculating axons. gp160Dtrk has structural homology with neural cell adhesion molecules of the immunoglobulin superfamily and… CONTINUE READING