Dry mouth with conventional and controlled-release oxybutynin in urinary incontinence. The Ditropan XL Study Group.

@article{Versi2000DryMW,
  title={Dry mouth with conventional and controlled-release oxybutynin in urinary incontinence. The Ditropan XL Study Group.},
  author={Eboo Versi and Rodney Appell and David Mobley and William C. Patton and Daniel R. Saltzstein},
  journal={Obstetrics and gynecology},
  year={2000},
  volume={95 5},
  pages={718-21}
}
OBJECTIVE To compare the efficacy and safety of controlled-release oxybutynin with conventional, immediate-release oxybutynin and determine rates of dry mouth. METHODS Patients (n = 226) who were known to be responsive to anticholinergic therapy and who had seven or more urge incontinence episodes per week were randomized to receive controlled-release oxybutynin or immediate-release oxybutynin. After an initial placebo run-in period, dosing in each began at 5 mg per day and increased weekly… CONTINUE READING

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