Dry Eye Disease
@article{PinhoTavares2010DryED, title={Dry Eye Disease}, author={Fabiana de Pinho Tavares and Raphael Stehling Fernandes and Taliana Freitas Bernardes and Adriana Alvim Bonfioli and Eduardo Jorge Carneiro Soares}, journal={Seminars in Ophthalmology}, year={2010}, volume={25}, pages={84 - 93} }
Dry eye (DED) is a multifactorial disease that results in symptoms of discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface, accompanied by increased osmolarity of the tear film and inflammation. DED is a common clinical problem and is among the most frequent diagnoses in ophthalmology. It substantially affects quality of life because of the constant ocular discomfort and decrease in visual function. This review discusses the etiology…
47 Citations
Dry eye disease: A review of diagnostic approaches and treatments.
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The role of tear osmolarity is discussed in the diagnosis procedures of DED and its role in the pathogenesis and management has been an exciting issue.
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A literature review of published works on dry eye disease, evaluation, risk factors, and management found that the core of DED therapy is the use of over-the-counter ocular lubricants to enhance humidity at the ocular surface.
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The identification of distinct metabolites and integrated metabolic profiles in patients can potentially inform clinicians at an early stage or during monitoring of disease progression, enhancing diagnosis, prognosis, and the choice of therapy.
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Development of complex preparations, preservative-free and/or novel preservative preparations for glaucoma therapy could provide a promising approach in the prevention of ocular surface injuries.
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The importance of considering and carefully assessing the ocular surface for evidence of dry eye or other problems is highlighted, with the aim of enabling clinical intervention to prevent or retard the deleterious eff ect and exacerbation of ocularsurface disease by topical glaucoma medication.
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The efficacy and characteristics of Diquas and the mucin secretagogue Mucosta are summarized to improve the understanding of dry eye.
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The cytological analysis of conjunctival impression in 42 patients with dry eye syndrome established a strong correlation between the clinical grade of severity of disease and the grade of squamous metaplasia, including goblet cell loss.
Evaluation of the Ocular Surface Disease Index Questionnaire as a Discriminative Test for Clinical Findings in Dry Eye Disease Patients
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- 2019
Cut-off values for the OSDI can be defined to discriminate pathological TFBUT, OSS, ST, ST (≤5 and ≤10) and ME, however, the discriminability was low.
The relationship between dry eye and migraine
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- 2014
The results show that dry eye may present in migraine patients with greater presence of auras and longer disease and attack durations, and attack duration was found to be independently associated with the presence of dry eye in migraine Patients.
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