Dry Eye Disease

@article{PinhoTavares2010DryED,
  title={Dry Eye Disease},
  author={Fabiana de Pinho Tavares and Raphael Stehling Fernandes and Taliana Freitas Bernardes and Adriana Alvim Bonfioli and Eduardo Jorge Carneiro Soares},
  journal={Seminars in Ophthalmology},
  year={2010},
  volume={25},
  pages={84 - 93}
}
Dry eye (DED) is a multifactorial disease that results in symptoms of discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface, accompanied by increased osmolarity of the tear film and inflammation. DED is a common clinical problem and is among the most frequent diagnoses in ophthalmology. It substantially affects quality of life because of the constant ocular discomfort and decrease in visual function. This review discusses the etiology… 
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The cytological analysis of conjunctival impression in 42 patients with dry eye syndrome established a strong correlation between the clinical grade of severity of disease and the grade of squamous metaplasia, including goblet cell loss.
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The results show that dry eye may present in migraine patients with greater presence of auras and longer disease and attack durations, and attack duration was found to be independently associated with the presence of dry eye in migraine Patients.
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