Drugs of abuse as memory modulators: a study of cocaine in rats

@article{Rkieh2013DrugsOA,
  title={Drugs of abuse as memory modulators: a study of cocaine in rats},
  author={Nabeel Rkieh and Jacob M. Cloke and Nicola Palamero Gallagher and Boyer D. Winters and Francesco Leri},
  journal={Psychopharmacology},
  year={2013},
  volume={231},
  pages={2339-2348}
}
It has been proposed that drugs of abuse reinforce behavior partly, or wholly, because they facilitate learning by enhancing memory consolidation. Cocaine can clearly serve as a reinforcer, but its effect on learning has not been fully characterized. To explore the effects of different regimens of pre- and post-training cocaine administration on win-stay and object learning. Cocaine naïve and cocaine pre-exposed (30 mg/kg/day, ×5 days followed by 7 days drug-free) male Sprague-Dawley rats… CONTINUE READING

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