Drugs for Acute Attack of Pediatric Migraine: A Network Meta-analysis of Randomized Controlled Trials

@article{Wang2020DrugsFA,
  title={Drugs for Acute Attack of Pediatric Migraine: A Network Meta-analysis of Randomized Controlled Trials},
  author={Guihua Wang and Tianlin Tan and Yao Liu and Peiwei Hong},
  journal={Clinical Neurology and Neurosurgery},
  year={2020},
  volume={195}
}
Migraine in pediatric is a common neurological disease, and its prevalence is varying widely. The medication for the acute attack of pediatric migraine is various. we take advantage of network meta-analysis to address the efficacy and rank of these medications. Database including Pubmed and Cochrane Library were queried using a specific searching strategy. The quality of trials enrolled was assessed according to the Cochrane collaboration'tool for assessing risk of bias. The data analysis was… Expand
Paracetamol versus Ibuprofen for the Acute Treatment of Migraine Headache in Children: A Blinded Randomized Controlled Trial - Correspondence
TLDR
It is found that both drugs are equally efficacious for acute attacks of migraine, although the study has several limitations including inadequate blinding, small sample size, study design covering single attack only, without any cross over of drugs, as pointed out by authors themselves. Expand

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