Drugs and Polymers for Delivery Systems in OA Joints: Clinical Needs and Opportunities

@inproceedings{Janssen2014DrugsAP,
  title={Drugs and Polymers for Delivery Systems in OA Joints: Clinical Needs and Opportunities},
  author={Maarten Janssen and George Mihov and Tim J. M. Welting and Jens Christoph Thies and Pieter Emans},
  year={2014}
}
Osteoarthritis (OA) is a big burden of disease worldwide and one of the most common causes of disability in the adult population. Currently applied therapies consist of physical therapy, oral medication, intra-articular injections, and surgical interventions, with the main goal being to reduce pain and improve function and quality of life. Intra-articular (IA) administration of drugs has potential benefits in OA treatment because it minimizes systemic bioavailability and side effects associated… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 94 REFERENCES

An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis.

  • Journal of controlled release : official journal of the Controlled Release Society
  • 2013
VIEW 1 EXCERPT

Epidemiology of osteoarthritis.

  • Rheumatic diseases clinics of North America
  • 2013
VIEW 1 EXCERPT