Drug treatment of epilepsy in the century of the ILAE: The second 50 years, 1959–2009

@article{Shorvon2009DrugTO,
  title={Drug treatment of epilepsy in the century of the ILAE: The second 50 years, 1959–2009},
  author={S. Shorvon},
  journal={Epilepsia},
  year={2009},
  volume={50}
}
The drug therapy of epilepsy evolved enormously in this 50 year period. Advances in therapeutics included the incorporation of pharmacokinetics into clinical practice, enormous advances in neurochemistry, a trend to antiepileptic drug monotherapy, better drug assessment, better understanding of therapeutic outcomes, and the recognition of the large epilepsy treatment gap in many countries. An unprecedented range of new drugs was introduced in this period. Before 1989, these included… Expand
97 Citations
Antiepileptic Drugs Under Investigation for Treatment of Focal Epilepsy
  • 6
Highights in the History of Epilepsy: The Last 200 Years
  • 47
  • PDF
The evolution of antiepileptic drug development and regulation
  • 46
  • PDF
Modern antiepileptic drug development has failed to deliver: Ways out of the current dilemma
  • 397
  • Highly Influenced
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 273 REFERENCES
Principles for Clinical Testing of Antiepileptic Drugs
  • 20
Monotherapy or polytherapy for epilepsy?
  • A. Guberman
  • Medicine
  • The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
  • 1998
  • 88
  • PDF
Ethosuximide in the treatment of epilepsy.
  • 55
Results of treatment changes in patients with apparently drug‐resistant chronic epilepsy
  • 284
We Live in the Age of the Clinical Guideline
  • 12
Double-blind study of vigabatrin in the treatment of drug-resistant epilepsy.
  • 130
The temporal aspects of prognosis in epilepsy.
  • S. Shorvon
  • Medicine
  • Journal of neurology, neurosurgery, and psychiatry
  • 1984
  • 95
  • PDF
A new drug for petit mal epilepsy
  • 81
...
1
2
3
4
5
...