Drug transporter expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line.

@article{Januchowski2014DrugTE,
  title={Drug transporter expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line.},
  author={Radosław Januchowski and Piotr Zawierucha and Marcin Rucinski and Małgorzata Andrzejewska and Karolina Wojtowicz and Michał Nowicki and Maciej Zabel},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={2014},
  volume={68 4},
  pages={447-53}
}
Ovarian cancer is characterized by the higher mortality among gynecological cancers. In results of MDR development during chemotherapy cancer cells become resistant to further treatment. Microarray techniques can provide information about MDR development at gene expression level. ABC and SLC transporters are most important proteins responsible for this phenomenon. In this study changes of ABC and SLC genes expression pattern in drugs resistant sublines of the A2780 ovarian cancer cell line were… CONTINUE READING
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ABCC2 (MRP2, cMOAT) can be localized in the nuclear Please cite this article in press as: Januchowski R, et al. Drug transpo ovarian cancer cell line

  • P Surowiak, V Materna, I Kaplenko, M Spaczynski, B Dolinska-Krajewska, E Gebarowska
  • Biomed Pharmacother
  • 2014
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