Drug-target interaction prediction: databases, web servers and computational models

@article{Chen2016DrugtargetIP,
  title={Drug-target interaction prediction: databases, web servers and computational models},
  author={Xing Chen and Chenggang Clarence Yan and Xiaotian Zhang and Xu Zhang and Feng Dai and Jian Yin and Yongdong Zhang},
  journal={Briefings in bioinformatics},
  year={2016},
  volume={17 4},
  pages={696-712}
}
Identification of drug-target interactions is an important process in drug discovery. Although high-throughput screening and other biological assays are becoming available, experimental methods for drug-target interaction identification remain to be extremely costly, time-consuming and challenging even nowadays. Therefore, various computational models have been developed to predict potential drug-target associations on a large scale. In this review, databases and web servers involved in drug… CONTINUE READING
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