Drug sensor: liposome immunosensor for theophylline.

  title={Drug sensor: liposome immunosensor for theophylline.},
  author={Makoto Haga and Shunji Sugawara and Hiroshi Itagaki},
  journal={Analytical biochemistry},
  volume={118 2},
Abstract A new simple, sensitive liposome immunosensor has been developed by combining the advantages of spin membrane immunoassay and enzyme immunosensor. Theophylline, which is widely used in the treatment of acute and chronic respiratory diseases, was chosen as a model molecule. The liposome immunosensor system is composed of a Clark-type oxygen electrode and actively sensitized liposomes. It records liposome lysis induced by specific antitheophlline antibodies and complement which are… CONTINUE READING