Drug screening of preserved oral fluid by liquid chromatography-tandem mass spectrometry.

@article{iestad2006DrugSO,
  title={Drug screening of preserved oral fluid by liquid chromatography-tandem mass spectrometry.},
  author={Elisabeth Leere {\O}iestad and Unni Johansen and Asbjorg Solberg Christophersen},
  journal={Clinical chemistry},
  year={2006},
  volume={53 2},
  pages={
          300-9
        }
}
BACKGROUND Oral fluid is an alternative matrix with potential applications in road-side drug screening, work-place testing, drug treatment programs, and epidemiological surveys. Development of methods for extensive drug screening in oral fluid is warranted. METHODS We developed a liquid chromatography- tandem mass spectrometry (LC-MS/MS) method for drug screening of preserved oral fluid collected with the Intercept collection device. Samples were prepared by liquid-liquid extraction with… CONTINUE READING
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