Drug safety surveillance using de-identified EMR and claims data: issues and challenges

@article{Nadkarni2010DrugSS,
  title={Drug safety surveillance using de-identified EMR and claims data: issues and challenges},
  author={Prakash M. Nadkarni},
  journal={Journal of the American Medical Informatics Association : JAMIA},
  year={2010},
  volume={17 6},
  pages={
          671-4
        }
}
The author discusses the challenges of pharmacovigilance using electronic medical record and claims data. Use of ICD-9 encoded data has low sensitivity for detection of adverse drug events (ADEs), because it requires that an ADE escalate to major-complaint level before it can be identified, and because clinical symptomatology is relatively under-represented in ICD-9. A more appropriate vocabulary for ADE identification, SNOMED CT, awaits wider deployment. The narrative-text record of progress… CONTINUE READING
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