Drug resistance factors in acute myeloid leukemia: a comparative analysis

@article{Filipits2000DrugRF,
  title={Drug resistance factors in acute myeloid leukemia: a comparative analysis},
  author={Martin Filipits and Thomas Stranzl and Gudrun Pohl and Harald Heinzl and Ulrich Dr Jaeger and Klaus Geissler and Christa Fonatsch and O. E. Haas and Klaus Lechner and Robert Pirker},
  journal={Leukemia},
  year={2000},
  volume={14},
  pages={68-76}
}
To compare the clinical relevance of drug resistance factors in de novo acute myeloid leukemia (AML), we determined their relationship to both response to induction chemotherapy and survival of the patients in univariate as well as multivariate analyses. The drug resistance factors immunocytochemically studied in 111 patients at the time of diagnosis included the lung resistance protein (LRP), P-glycoprotein (P-gp), multidrug resistance protein (MRP1) and bcl-2. In the univariate analyses, age… CONTINUE READING
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