Drug release properties of polyethylene-glycol-treated ciprofloxacin-Indion 234 complexes

@article{Pisal2004DrugRP,
  title={Drug release properties of polyethylene-glycol-treated ciprofloxacin-Indion 234 complexes},
  author={Sambhaji S Pisal and Rana Zainnuddin and Pradeep Nalawade and Kakasaheb Mahadik and Shivajirao S. Kadam},
  journal={AAPS PharmSciTech},
  year={2004},
  volume={5},
  pages={101-106}
}
The polyethylene glycol (PEG) treatment of ciprofloxacin-Indion 234 complex was aimed to retard rapid ion exchange drug release at gastric pH. Ciprofloxacin loading on Indion 234 was performed in a batch process, and the amount of K+ in Indion 234 displaced by drug with time was studied as equilibrium constant KDM. Drug-resin complex (DRC) was treated with… CONTINUE READING