Drug loading into porous calcium carbonate microparticles by solvent evaporation.

Abstract

Drug loading into porous carriers may improve drug release of poorly water-soluble drugs. However, the widely used impregnation method based on adsorption lacks reproducibility and efficiency for certain compounds. The aim of this study was to evaluate a drug-loading method based on solvent evaporation and crystallization, and to investigate the underlying… (More)
DOI: 10.1016/j.ejpb.2014.02.009

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