Drug-ionic channel interactions: single-channel measurements.


Ionic channels of excitable membranes are the basic site where ionic fluxes take place during the generation of action potentials. A variety of natural toxins, chemicals, and therapeutic drugs have been found to modify the gating kinetics of the Na+ channels, thereby altering the excitation pattern. Studies of such chemical modulations of Na+ channel gating… (More)


Cite this paper

@article{Narahashi1984DrugionicCI, title={Drug-ionic channel interactions: single-channel measurements.}, author={Toshio Narahashi}, journal={Annals of neurology}, year={1984}, volume={16 Suppl}, pages={S39-51} }