Drug interaction between infliximab and azathioprine in patients with Crohn's disease.

@article{Roblin2003DrugIB,
  title={Drug interaction between infliximab and azathioprine in patients with Crohn's disease.},
  author={Xavier Roblin and Françoise Serre-Debeauvais and J. Phelip and Germain Bessard and Bruno Bonaz},
  journal={Alimentary pharmacology & therapeutics},
  year={2003},
  volume={18 9},
  pages={
          917-25
        }
}
BACKGROUND A drug interaction has been observed between infliximab and methotrexate in rheumatoid arthritis. AIM To look for an interaction between infliximab and azathioprine in Crohn's disease patients using the active metabolites of azathioprine: 6-tioguanine nucleotides. METHODS Patients receiving azathioprine who required infliximab for ileo-colonic or ano-perineal Crohn's disease were recruited prospectively. 6-tioguanine nucleotide levels were evaluated before infusion, within 1-3… CONTINUE READING
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