Drug-induced hypochlorhydria causes high duodenal bacterial counts in the elderly.

@article{Pereira1998DruginducedHC,
  title={Drug-induced hypochlorhydria causes high duodenal bacterial counts in the elderly.},
  author={Susana Pereira and Nicola Gainsborough and R. Hermon Dowling},
  journal={Alimentary pharmacology & therapeutics},
  year={1998},
  volume={12 1},
  pages={99-104}
}
BACKGROUND Small bowel bacterial overgrowth secondary to drug-induced hypochlorhydria may be of particular importance in the elderly, in whom anti-ulcer drugs are commonly prescribed and the consequences of malabsorption may be severe. METHODS Duodenal aspirates were obtained from elderly individuals before (n = 24) and during a 2-month treatment course with either omeprazole (20 mg daily; n = 8) or ranitidine (300 mg b.d.; n = 6), and from six patients with small bowel bacterial overgrowth… CONTINUE READING